In Brown and Lostroh (submitted), we present models for inferring gene
activity dynamics from reporter protein time series data. The
method is implemented in the following Excel spreadsheets. The
first one is general, valid for any system in which the reporter
protein is detectable immediately upon synthesis. The second one
is specific for GFP, incoporating a transitional period before the
fluorescent. For details on the models and assumptions, please
see the paper. Each spreadsheet contains brief instructions in
comment boxes. Please feel free to download and use these
spreadsheets, citing the paper by Brown and Lostroh (submitted).
Spreadsheet for general model.
Spreadsheet for GFP model.
If you have questions, please contact David Brown at: