Chemistry 345:Bioanalytical Chemistry
Block 6, 2009
Tentative Syllabus

Professor: Howard Drossman
Technical Director: Matt Reuer

 

   

Topic

Reading

Assns. Due

WEEK 1

Week 1 Reading Notes

Day 1

AM

Class Introduction
Cookie Lab
Pipette Calibration (#1)

Chs. 1 & 2
Lab Manual

 
PM

Pipette Calibration (#1)

Day 2

AM

Statistics
Excel Data Analysis (Lab 1)

Chapter 3-4

 
PM

Soil Extraction

Excel Data Analysis (cont.)

Lab Manual

Day 3

AM

Experimental Design & ANOVA
Cookie Lab Data

Chs. 0, 5, handout

 
PM

Protein Determination in Soils (L2)

Lab Manual

Day 4

AM

Linear Regression
Excel Data Analysis (L2)

Lab 1 Due
Ch. 4

 
PM

ANOVA Worksheet (A1; Protein Soil Data)
Intro to Optimization (Barnes PC Lab)

Lab Manual

Day 5

AM

Chemical Activity (POGIL), Acid/Base & Buffers I (worksheet)
Animated Alpha Diagrams

Chs. 6, 8, 10

 
PM

Acid/Base Spreadsheet (A2)

Lab Manual

Literature Exam I

WEEK 2

Week 2 Reading Notes

Day 1

AM

Acid/Base II & Complexation

Chs. 10, 12, 13
Exam Due (9 AM)

 
PM

Clinical Analysis (Project 1)

 

Day 2

AM

Separations I
Computer Protein Separations (A3)
Separations link (Barnes PC Lab)

Chapter 23
A2; L2 Due

 
PM

Clinical Analysis (P1)

 

Day 3

AM

Separations II: Thermo & Resolution (worksheet)

Chs. 23, 25

A2 Due

 
PM

Clinical Analysis (P1)

 

Day 4

AM

Separations III : Diffusion   (worksheet, POGIL)

LC Optimization

Genome Papers 1, 2

 
PM

Clinical Analysis (P1)

 

Day 5

AM

Genome Sequencing I: Introduction & Overview

Electroseparations (worksheet),

CE  Sequencing (POGIL)

A3 Due

Genome Papers 3, 4, 5

 
PM

Project I Initial Data Analysis Due

Weekend Exam:

Genome Paper POGIL

WEEK 3

Week 3 Reading Notes

Day 1

AM

Genome Sequencing: Mass Spectrometry (POGIL)

Genome Papers 6, 7

PM

Lab Project II

 

Day 2

AM

Absorption, Emission and Single Molecule Detection (POGIL)

Genome Paper 8

Genome Papers 9, 10

PM

Lab Project II

 

Day 3

AM

Student Presentation I: Pyrosequencing (POGIL)

Student Presentation II: Nanopore sequencing (POGIL)

PM

Lab Project II
Spectroscopy Practicum (A4)

Lab Manual

Day 4

AM

Genome Sequencing: Sinusoidal CV (POGIL)

Student Presentations IV: Polonies (POGIL)

Genome Papers 15, 16

Genome Papers 17, 18

PM

Lab Project II

 

Day 5

AM

Student Presentation IV: Sequencing by synthesis (POGIL)

Student Presentation V: Single Molecules in nanoprores (POGIL)

PM

Chemistry Review?

Final Exam (weekend)
   

WEEK 4

 

Day 1

A/PM

Experimental Design Lab (P3)

Lab Manual

Day 2

A/PM

Experimental Design Lab (P3)

 
Day 3
PM

Project Presentations
Lab Clean Up


Text: Dan Harris, Quantitative Chemical Analysis, Seventh edition, Freeman


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